(R)-4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine CAS 1416348-77-0
| CAS No. | 1416348-77-0 |
| Molecular Formula | C10H17F3N2 |
| Molecular Weight | 222.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (R)-4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(R)-4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine (CAS 1416348-77-0), molecular formula C10H17F3N2 and molecular weight 222.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (R)-4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine (C10H17F3N2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H17F3N2 |
| Molecular Weight | 222.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related R Standards
- Trifluoromethyl benzodithioate (CAS 105501-63-1)
- 4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine (CAS 1335116-40-9)
- (S)-4-[2-(Trifluoromethyl)-1-pyrrolidinyl]-piperidine (CAS 1416348-90-7)
- 3-[4-(trifluoromethyl)piperidin-1-yl]cyclobutan-1-amine (CAS 1517845-90-7)
- 2-methyl-6-(trifluoromethyl)quinoxaline (CAS 646512-72-3)
- (4-((Trifluoromethyl)thio)benzyl)hydrazine (CAS 1016529-12-6)
- N-((2-(trifluoromethyl)thiazol-4-yl)methyl)cyclopropanamine (CAS 1420887-68-8)
- 1-{4-[(trifluoromethyl)sulfanyl]phenyl}ethan-1-ol (CAS 21101-66-6)
Recommended Standards
- (E)-1,1,1-Trifluoroundec-3-en-2-one (CAS 1399772-69-0)
- 4-(Pyridin-4-yl)phthalazin-1-amine (CAS 139328-94-2)
- 147330-32-3 5-[1,1'-Biphenyl]-2-yl-1H-tetrazole 5-[1,1'-Biphenyl]-2-yl-2H-tetrazole L 809022 (CAS 147330-32-3)
- Ethyl 4,4-diethoxy-2-fluorobutanoate (CAS 1384431-26-8)
- 2-Furancarbonitrile, 3-fluoro- (CAS 2122319-19-9)
- 2-Furoyl chloride (CAS 527-69-5)
- 2-Chloro-5-(difluoromethyl)-6-methoxynicotinonitrile (CAS 1806926-67-9)
- N-butyl-6-(4-chlorophenoxy)hexan-1-amine (CAS 418785-46-3)
- Dorzolamide Impurity 22 (CAS 147128-79-8)
- (3aS,5aS,8aR,8bR)-2,7-Diethyltetrahydro-5H-thiopyrano[2,3-d:4,5-d']bis([1,3,2]dioxaborole) (CAS 74793-32-1)
- 5-Ethyl-1-methyl-3-(3-nitrophenyl)-1H-1,2,4-triazole (CAS 1416440-36-2)
- (2-Chloro-4,5-dimethoxyphenyl)methanamine (CAS 1246471-50-0)
- 2-((2-Fluorobenzyl)thio)acetohydrazide (CAS 669705-47-9)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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