Dorzolamide Impurity 22 CAS 147128-79-8
| CAS No. | 147128-79-8 |
| Molecular Formula | C10H14N2O5S3 |
| Molecular Weight | 338.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Dorzolamide Impurity 22 (CAS 147128-79-8), a pharmacopoeial impurity reference standard (molecular formula C10H14N2O5S3, MW 338.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H14N2O5S3, Dorzolamide Impurity 22 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 338.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Dorzolamide Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O5S3 |
| Molecular Weight | 338.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Dorzolamide Standards
- Dorzolamide Impurity 5 (CAS CATO-C4X-12285)
- Dorzolamide N-Desethyl N-Acetyl Impurity (CAS 147200-03-1)
- Dorzolamide-d5 (CAS 1227097-70-2)
- Dorzolamide Impurity 13 (CAS 897657-78-2)
- Dorzolamide (CAS 120279-96-1)
- Rac-Dorzolamide (CAS 120280-13-9)
- Dorzolamide (CAS 139066-77-6)
- Dorzolamide EP Impurity B（R,S-Isomer) (CAS 149249-72-9)
Recommended Standards
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- Tamoxifen Impurity 11 (CAS 5435-24-5)
- N1-((1,4-Dioxaspiro[4.5]decan-2-yl)methyl)-N2-(thiophen-2-ylmethyl)oxalamide (CAS 899957-96-1)
- Prucalopride Impurity 41（DP-4） (CAS 1900715-95-8)
- Mirtazapine EP Impurity C (CAS 191546-96-0)
- Phenytoin EP Impurity A (CAS 119-61-9)
- 3,5-dichloro-2-hydroxy-n-isobutylbenZamide (CAS 100127-25-1)
- Tert-butyl (2-chloro-5-sulfamoylphenyl)carbamate (CAS 889856-21-7)
- 4-Acetamido-2-methyltetrahydro-2h-pyran-4-carboxylic acid (CAS 1339020-23-3)
- 3,4-Bis(methylthio)phenol (CAS 1243459-20-2)
- 3-Methyl-2,2-diphenylbutanoic acid (CAS 80743-47-1)
- 2-Ethyl-1,2-dihydro-3h-1,2,4-triazol-3-imine hydrochloride (CAS 1255717-34-0)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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