Methyl 5-cyclopropyl-2-(4-methoxyphenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate CAS 1416439-75-2
| CAS No. | 1416439-75-2 |
| Molecular Formula | C21H21NO6S |
| Molecular Weight | 415.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-cyclopropyl-2-(4-methoxyphenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate.
Methyl 5-cyclopropyl-2-(4-methoxyphenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate (CAS 1416439-75-2), molecular formula C21H21NO6S and molecular weight 415.46 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 5-cyclopropyl-2-(4-methoxyphenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate (C21H21NO6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 5-cyclopropyl-2-(4-methoxyphenyl)-6-(methylsulfonamido)benzofuran-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H21NO6S |
| Molecular Weight | 415.46 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- N-Cyclopropyl-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine-5-carboxamide (CAS 477859-54-4)
- (5-Cyclopropyl-isoxazol-4-yl)-[2,5-dimethyl-4-oxazol-2-yl-3-(propane-1-sulfonyl)-phenyl]-methanone (CAS 1231570-52-7)
- (5-Cyclopropyl-isoxazol-4-yl)-[2,5-dimethyl-3-oxazol-2-yl-4-(propane-1-sulfonyl)-phenyl]-methanone (CAS 1231604-27-5)
- 2-({[4-cyclopropyl-6-(methylthio)-1,3,5-triazin-2-yl]amino}methylidene)-4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione (CAS 649578-95-0)
- N-(1-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)cyclohexyl)-2-(3,4-diethoxyphenyl)acetamide (CAS 1396633-24-1)
- Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(4-methoxyphenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-35-8)
- P-[[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]phosphonic acid diethyl ester (CAS 154057-57-5)
- 1-Cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 144633-80-7)
Recommended Standards
- Fmoc-S-carboxyethyl-L-cysteine (CAS 1354488-30-4)
- 2,2,4-Trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1820889-23-3)
- Acalabrutinib Impurity 16 (CAS 2230757-50-1)
- (11bS)-N,N-Bis(1-methylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 185449-85-8)
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclopentanamine (CAS 1704150-93-5)
- 2-Chloro-6-(4-methoxyphenyl)-4-methylnicotinonitrile (CAS 943115-23-9)
- 1806766-03-9 3-(Difluoromethyl)-2-hydroxypyridine (CAS 1806766-03-9)
- N-(4-(Benzyl(methyl)amino)but-2-yn-1-yl)-3-phenylpropanamide (CAS 1396803-41-0)
- 4’-Bromo-3-iodo-1,1’-biphenyl (CAS 130201-21-7)
- N-(3-cyano-4-(methylsulfinyl)phenyl)-3-(trifluoromethyl)benzamide (CAS 320421-30-5)
- 3-Fluoro-5-nitropyridin-4-ol (CAS 1806294-57-4)
- 4-Amino-3-((triisopropylsilyl)ethynyl)benzoic acid (CAS 2834081-10-4)
- 6-(Boc-amino)-2,2-dimethylchroman-4-one (CAS 1314406-17-1)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com