Ethyl 3-bromo-6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate CAS 1416440-26-0
| CAS No. | 1416440-26-0 |
| Molecular Formula | C10H7BrF2N2O2 |
| Molecular Weight | 305.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-bromo-6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate.
Ethyl 3-bromo-6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1416440-26-0), molecular formula C10H7BrF2N2O2 and molecular weight 305.08 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 3-bromo-6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate (C10H7BrF2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 305.08 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 3-bromo-6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7BrF2N2O2 |
| Molecular Weight | 305.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
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