6-Bromo-2-(difluoromethyl)-8-methylimidazo[1,2-a]pyridine-3-carboxylic acid CAS 2451256-46-3
| CAS No. | 2451256-46-3 |
| Molecular Formula | C10H7BrF2N2O2 |
| Molecular Weight | 305.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-Bromo-2-(difluoromethyl)-8-methylimidazo[1,2-a]pyridine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 6-Bromo-2-(difluoromethyl)-8-methylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 2451256-46-3), a certified reference material (molecular formula C10H7BrF2N2O2, MW 305.08 g/mol) for analytical method development and quality control.
6-Bromo-2-(difluoromethyl)-8-methylimidazo[1,2-a]pyridine-3-carboxylic acid (C10H7BrF2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7BrF2N2O2 |
| Molecular Weight | 305.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
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Recommended Standards
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- 2-Bromo-3-cyclopropoxy-5-isopropylpyridine (CAS 1243444-34-9)
- 4-Cyclopropoxy-N2,N5,N5-trimethylpyridine-2,5-diamine (CAS 1243403-25-9)
- 7-bromo-4-chloroimidazo[2,1-f][1,2,4]triazine (CAS 1235374-46-5)
- N-(2-Hydroxyethyl)methacrylamide (CAS 5238-56-2)
- 4-(2-Phenoxyacetyl)piperazin-2-one (CAS 587850-66-6)
- 2,3-Dichloro-6-nitrobenzyl Alcohol (CAS 393078-37-0)
- 5-Bromo-2'-chloro-2,3'-bipyridine (CAS 942205-99-4)
- N-(4-Amino-3-methoxyphenyl)methanesulfonamidehydrochloride (CAS 83209-83-0)
- Bevantolol Impurity 21 (CAS CATO-C4X-241121)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com