4-Fluoro-3-methyl-1H-indole-2-carboxylic acid CAS 1417357-90-4

Description

4-Fluoro-3-methyl-1H-indole-2-carboxylic acid (CAS 1417357-90-4), molecular formula C10H8FNO2 and molecular weight 193.17 g/mol, is a CATO reference standard with documented purity and traceability.

4-Fluoro-3-methyl-1H-indole-2-carboxylic acid (C10H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Fluoro-3-methyl-1H-indole-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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