Irbesartan Impurity 12 CAS 141745-36-0
| CAS No. | 141745-36-0 |
| Molecular Formula | C23H26N6O |
| Molecular Weight | 402.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Irbesartan Impurity 12 (CAS 141745-36-0), a pharmacopoeial impurity reference standard (molecular formula C23H26N6O, MW 402.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Irbesartan Impurity 12 (C23H26N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 402.49 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Irbesartan Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H26N6O |
| Molecular Weight | 402.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 6 |
Related Irbesartan Standards
- Irbesartan Impurity 30 (CAS 141745-71-3)
- Irbesartan Impurity 22 (CAS CATO-C4X-166622)
- Irbesartan Impurity 41 (CAS CATO-C4X-166641)
- Irbesartan Impurity 10 (CAS 1312996-19-2)
- Irbesartan Impurity 26 (CAS CATO-C4X-166626)
- Irbesartan Impurity 45 (CAS CATO-C4X-166645)
- Irbesartan Impurity 7 (CAS 138401-24-8)
- Irbesartan impurity 40 (CAS CATO-C4X-166640)
Recommended Standards
- Eltrombopag Impurity 73 (CAS CATO-C4X-119873)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com