Osimertinib Impurity 73 CAS CATO-C4X-204573

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-204573
Molecular FormulaC23H26N6O
Molecular Weight402.49 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Osimertinib Impurity 73 CAS CATO-C4X-204573 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

As a process- or degradation-related impurity, Osimertinib Impurity 73 (CAS CATO-C4X-204573, C23H26N6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Osimertinib Impurity 73 (C23H26N6O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC23H26N6O
Molecular Weight402.49 g/mol
AppearancePale yellow to yellow crystalline powder
Purity≥95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms6

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