Triamcinolone Acetonide Impurity 48 CAS 1418196-53-8
| CAS No. | 1418196-53-8 |
| Molecular Formula | C26H32O7 |
| Molecular Weight | 456.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Triamcinolone Acetonide Impurity 48 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 456.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Triamcinolone Acetonide Impurity 48 (CAS 1418196-53-8), a pharmacopoeial impurity reference standard (molecular formula C26H32O7, MW 456.53 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H32O7 |
| Molecular Weight | 456.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
Related Triamcinolone Standards
- Triamcinolone Acetonide Impurity 46 (CAS CATO-C4X-132646)
- Triamcinolone Acetonide EP Impurity D (CAS 10392-74-2)
- Triamcinolone Acetonide RC 3 (CAS 3924-70-7)
- Triamcinolone Acetonide EP Impurity C (CAS 161740-69-8)
- Triamcinolone Impurity 40 (CAS CATO-C4X-132640)
- Triamcinolone Acetonide RC 7 (CAS 68263-02-5)
- Triamcinolone Acetonide Impurity 49 (CAS 7704-77-0)
- Triamcinolone Acetonide Impurity 38 (CAS CATO-C4X-132638)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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