Tulobuterol Impurity 12 CAS 14185-28-5
| CAS No. | 14185-28-5 |
| Molecular Formula | C12H18ClNO |
| Molecular Weight | 227.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tulobuterol Impurity 12 (CAS 14185-28-5) is a certified pharmaceutical impurity reference standard with the molecular formula C12H18ClNO and a molecular weight of 227.73 g/mol.
Structurally, Tulobuterol Impurity 12 (C12H18ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 227.73 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tulobuterol Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18ClNO |
| Molecular Weight | 227.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tulobuterol Standards
- Tulobuterol Impurity 10 (CAS 69240-94-4)
- Tulobuterol Impurity 8 (CAS 69240-90-0)
- Tulobuterol (CAS 41570-61-0)
- Tulobuterol Impurity N9 (CAS 41011-01-2)
- Tulobuterol Impurity N1 (CAS 5000-66-8)
- Tulobuterol Impurity N2 (CAS 536-38-9)
- Tulobuterol Impurity 23 (CAS CATO-C4X-213423)
- Tulobuterol Impurity 5 (CAS 6314-52-9)
Recommended Standards
- 67746-96-7 7964AE C12H18ClNO N-[2-(4-Chlorophenoxy)ethyl]-1-butanamine (CAS 67746-96-7)
- n-(3-Chlorobenzyl)-3-ethoxypropan-1-amine (CAS 705955-77-7)
- 4-((4-Chlorophenyl)thio)piperidine (CAS 101768-63-2)
- n-(2-Chlorobenzyl)-3-ethoxypropan-1-amine (CAS 705955-72-2)
- Trelagliptin impurity 71 (CAS 2204313-60-8)
- Lercanidipine Impurity 7 (CAS 100442-33-9)
- Linagliptin Impurity 62 (CAS 1807608-59-8)
- 3,3',3''-Phosphinetriyltributanenitrile (CAS 64581-11-9)
- (e)-trimethyl(3-phenylbut-2-en-1-yl)silane (CAS 79239-05-7)
- 2-Ethyl[1,3]oxazolo[5,4-b]pyridine-6-carboxylic acid (CAS 927801-28-3)
- 1,1-Difluoro-4-trifluoromethyl-cyclohexane (CAS 1416351-96-6)
- 1,3-dichloropentane (CAS 30122-12-4)
- [1,1'-Bi(cyclohexan)]-1'-en-2-one (CAS 1502-22-3)
- Semaglutide impurity 103 (CAS 1446013-07-5)
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