Losartan Impurity 60 CAS 141949-89-5
| CAS No. | 141949-89-5 |
| Molecular Formula | C22H24ClN7 |
| Molecular Weight | 421.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Losartan Impurity 60.
Losartan Impurity 60 (CAS 141949-89-5) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24ClN7 and a molecular weight of 421.93 g/mol.
Losartan Impurity 60 (C22H24ClN7) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Losartan Impurity 60 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24ClN7 |
| Molecular Weight | 421.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Losartan Standards
Recommended Standards
- (2E)-2-(4-Chlorophenyl)-3-(dimethylamino)-1-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}prop-2-en-1-one (CAS 478032-53-0)
- rac Clopidogrel [(tert-Butylcarbonyl)oxy]methyl ester (CAS 1043913-82-1)
- 2-(4-Methoxyphenyl)-4,6-bis(trichloromethyl)-1,3,5-triazine (CAS 3584-23-4)
- 2-(2-{[(2-chlorophenyl)sulfanyl]methyl}-1H-1,3-benzimidazol-1-yl)-N-methyl-N-phenylacetamide (CAS 339101-10-9)
- Neratinib Impurity 8 (CAS 13991-36-1)
- Atrasentan Impurity 122 (CAS 173864-35-2)
- Tivozanib Impurity 16 (CAS CATO-C4X-340016)
- 5-Chloro-6-[(3,4-difluorophenyl)amino]pyridine-3-carbonitrile (CAS 1240526-18-4)
- 2-Amino-2-(2,4-dihydroxyphenyl)acetic acid (CAS 77197-69-4)
- 1,3,5-Trimethyl-n-(pyrrolidin-3-yl)-1h-pyrazole-4-sulfonamide (CAS 1837709-58-6)
- 3-(4-Nitrophenyl)-5,6-dihydro-4H-pyrrolo[1,2-c][1,2,3]triazole (CAS 1445792-50-6)
- Methyl 7-((3R)-5-oxo-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopent-1-en-1-yl)heptanoate (CAS 60934-42-1)
- 2-Amino-6-bromo-8-fluoro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1649478-38-5)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com