8-Fluoro-2,6-dimethylquinolin-5-amine CAS 1420790-27-7

Description

Compared with other compounds in its class, the molecular weight of 190.22 g/mol gives 8-Fluoro-2,6-dimethylquinolin-5-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 8-Fluoro-2,6-dimethylquinolin-5-amine (CAS 1420790-27-7), a certified reference material (molecular formula C11H11FN2, MW 190.22 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 8-Fluoro-2,6-dimethylquinolin-5-amine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 190.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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