8-Fluoro-2,7-dimethylquinolin-5-amine CAS 1420790-43-7

Description

Compared with other compounds in its class, the molecular weight of 190.22 g/mol gives 8-Fluoro-2,7-dimethylquinolin-5-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

8-Fluoro-2,7-dimethylquinolin-5-amine (CAS 1420790-43-7) is a high-purity analytical reference standard with the molecular formula C11H11FN2 and a molecular weight of 190.22 g/mol.

8-Fluoro-2,7-dimethylquinolin-5-amine (C11H11FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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