1,8-Naphthyridine-2-carboxylic acid hydrobromide CAS 1421454-22-9
| CAS No. | 1421454-22-9 |
| Molecular Formula | C9H6N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.07 g/mol gives 1,8-Naphthyridine-2-carboxylic acid hydrobromide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1,8-Naphthyridine-2-carboxylic acid hydrobromide (CAS 1421454-22-9), molecular formula C9H6N2O2HBr and molecular weight 255.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,8-Naphthyridine-2-carboxylic acid hydrobromide (C9H6N2O2HBr) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O2 HBr |
| Molecular Weight | 255.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Naphthyridine Standards
- 1,6-naphthyridine-3-carboxylic acid (CAS 1017793-59-7)
- 1,7-naphthyridine-5-carboxylic acid (CAS 1019115-06-0)
- 1-Methyl-1,6-naphthyridine-2,5(1H,6H)-dione (CAS 1023812-98-7)
- 1,6-Naphthyridine-8-carbonitrile (CAS 1023813-61-7)
- 1,6-Naphthyridine-5-carbonitrile, 2-chloro- (CAS 1023817-79-9)
- 2,7-Naphthyridine-4-carbaldehyde (CAS 10273-40-2)
- 1,8-Naphthyridine-3-carboxylic acid (CAS 104866-53-7)
- 1,7-Naphthyridine-8-carboxylic acid (CAS 1060816-77-4)
Recommended Standards
- 5-Chloro-2-fluoro-N-(3-methoxypropyl)benzamide (CAS 1090033-19-4)
- 2-(Cyclopent-2-en-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one (CAS 1090865-89-6)
- 2-amino-1-(3,4-difluorophenyl)ethan-1-ol hydrochloride (CAS 51337-08-7)
- Methyl 2-chloro-4-(4-fluorophenyl)benzoate (CAS 1820706-24-8)
- Cholic Acid Impurity 51 (CAS 146340-08-1)
- 4-Chloro-2-cyclopropoxybenzoic acid (CAS 1243448-10-3)
- 3-Amino-2-hydroxy-N,N,6-trimethylbenzamide (CAS 654683-53-1)
- 3-methoxypropyl isothiocyanate (CAS 17702-11-3)
- 4-{5-[(4-Nitrobenzyl)sulfanyl]-1,3,4-oxadiazol-2-yl}pyridine (CAS 441289-28-7)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com