Cholic Acid Impurity 51 CAS 146340-08-1
| CAS No. | 146340-08-1 |
| Molecular Formula | C24H38O4 |
| Molecular Weight | 390.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Cholic Acid Impurity 51 (CAS 146340-08-1, C24H38O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cholic Acid Impurity 51 (C24H38O4) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Cholic Acid Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H38O4 |
| Molecular Weight | 390.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
Related Cholic Standards
- Cholic Acid Impurity 14 (CAS CATO-C4X-116014)
- Cholic Acid Impurity 20 (CAS 24637-46-5)
- Cholic Acid Impurity 36 (CAS 24637-45-4)
- Cholic Acid Impurity 45 (CAS 63266-92-2)
- Cholic Acid Impurity 9 (CAS 5130-29-0)
- Cholic Acid Impurity 29 (CAS 2024612-46-0)
- Cholic acid Impurity 10 (CAS 570-62-7)
- Cholic acid Impurity 11 (CAS 84848-09-9)
Recommended Standards
- 3-Oxo-12α-hydroxy-5β-cholanoic Acid (CAS 4185-01-7)
- Aclidinium bromide Impurity 16 (CAS CATO-C4X-132516)
- Ursodeoxycholic Acid EP Impurity F (CAS 4651-67-6)
- Ursodeoxycholic Acid impurity 103 (CAS CATO-C4X-1422103)
- Avibactam Impurity 139 (CAS CATO-C4X-1348139)
- Buserelin EP Impurity D (CAS CATO-C4X-22124)
- Meropenem Impurity 53 (CAS CATO-C4X-130953)
- Ethyl 1-(o-tolyl)-1H-1,2,4-triazole-3-carboxylate (CAS 1245646-71-2)
- 4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane (CAS 325142-82-3)
- 2-Oxo-N-(piperidin-4-yl)-1,2-dihydropyridine-3-carboxamide (CAS 1098349-90-6)
- 1H-pyrrol-2-ylmethanethiol (CAS 89179-52-2)
- Linoleic Acid-1- (CAS 98353-71-0)
- Aziridin-1-yl(pyrazin-2-yl)methanone (CAS 73058-38-5)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com