Entecavir Impurity 60 CAS 142217-77-4
| CAS No. | 142217-77-4 |
| Molecular Formula | C32H33N5O4 |
| Molecular Weight | 551.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Entecavir Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Entecavir Impurity 60 (CAS 142217-77-4, C32H33N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C32H33N5O4, Entecavir Impurity 60 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 551.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C32H33N5O4 |
| Molecular Weight | 551.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 5 |
Related Entecavir Standards
- Entecavir Impurity 18 (CAS CATO-C4X-107718)
- Entecavir Impurity 61 (CAS 1907700-40-6)
- Entecavir Impurity 62 (CAS CATO-C4X-107762)
- Entecavir Impurity 63 (CAS CATO-C4X-107763)
- Entecavir Impurity 64 (CAS CATO-C4X-107764)
- Entecavir Impurity 69 (CAS CATO-C4X-107769)
- Entecavir Impurity 85 (CAS CATO-C4X-107785)
- Entecavir Intermediates â…§ (CAS 204845-95-4)
Recommended Standards
- Akti-1/2 (CAS 612847-09-3)
- Nifekalant impurity 4 (CAS CATO-C4X-27974)
- Venetoclax Impurity 96 (CAS CATO-C4X-249596)
- Venetoclax Impurity 73 (CAS CATO-C4X-249573)
- Etizolam Impurity 21 (CAS CATO-C4X-350921)
- Trelagliptin impurity 80 (CAS CATO-C4X-104680)
- Afoxolaner impurity 11 (CAS CATO-C4X-31381)
- 6-Chlorospiro[4H-3,1-benzoxazine-4,4-piperidin]-2(1H)-one (CAS 92926-63-1)
- 3-(4-Chloro-phenyl)-isoxazole-5-carboxylic acid ethyl ester 81282-12-4 82C124 (CAS 81282-12-4)
- 3-n-Octylpyrrole (CAS 118799-18-1)
- (S)-Oxiran-2-ylmethyl 4-nitrobenzenesulfonate (CAS 118712-60-0)
- 5-Nitro-2-picolinoylbenzoic acid (CAS 50585-83-6)
- 2-[(1-Adamantylmethyl)amino]ethanol hydrochloride (CAS 79750-20-2)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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