Afoxolaner impurity 11 CAS CATO-C4X-31381
| CAS No. | CATO-C4X-31381 |
| Molecular Formula | C9H3ClF6O |
| Molecular Weight | 276.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Afoxolaner impurity 11 (CAS CATO-C4X-31381) is a certified pharmaceutical impurity reference standard with the molecular formula C9H3ClF6O and a molecular weight of 276.56 g/mol.
Structurally, Afoxolaner impurity 11 (C9H3ClF6O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 276.56 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C9H3ClF6O |
| Molecular Weight | 276.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Afoxolaner Standards
- Afoxolaner Impurity 33 (CAS CATO-C4X-313733)
- Afoxolaner Impurity 10 (CAS CATO-C4X-313710)
- Afoxolaner impurity 3 (CAS CATO-C4X-31373)
- Afoxolaner Impurity 11 (CAS CATO-C4X-313711)
- Afoxolaner Impurity 27 (CAS 2382920-55-8)
- Afoxolaner impurity 2 (CAS CATO-C4X-31372)
- Afoxolaner Impurity 26 (CAS CATO-C4X-313726)
- Afoxolaner Impurity 1 (CAS 1125812-54-5)
Recommended Standards
- Palbociclib Impurity 67 (CAS 1823404-28-9)
- (1,3-Dithian-2-yl)triisopropylsilane (CAS 145251-89-4)
- Palbociclib Impurity 31 (CAS 733039-20-8)
- n-(4-Bromo-2-chlorobenzyl)-2-methylpropan-1-amine (CAS 1178687-51-8)
- Baclofen Impurity 84 (CAS CATO-C4X-101284)
- Afoxolaner Impurity 20 (CAS 1125812-60-3)
- Glycopyrronium Bromide Impurity 20 (CAS CATO-C4X-181720)
- (1S,2S,4S,5R)-1-(anthracen-9-ylmethyl)-2-((R)-methoxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium iodide (CAS 374562-79-5)
- 5-Bromo-6-chloroquinoline (CAS 16560-60-4)
- 4-(tert-Butyl)-2-(5,6,7,8-tetrahydroquinolin-2-yl)-4,5-dihydrooxazole (CAS 2303959-54-6)
- N-(2-Iodophenyl)-4-methoxybenzenesulfonamide (CAS 346689-84-7)
- 1-(Furan-3-yl)cyclopropan-1-amine hydrochloride (CAS 1401425-27-1)
- 6-Bromopyridazin-4-ol (CAS 1956385-67-3)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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