Dabigatran Impurity 71 CAS 1422435-40-2
| CAS No. | 1422435-40-2 |
| Molecular Formula | C19H20N4O3 |
| Molecular Weight | 352.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dabigatran Impurity 71 (CAS 1422435-40-2) is a certified pharmaceutical impurity reference standard with the molecular formula C19H20N4O3 and a molecular weight of 352.39 g/mol.
The molecular framework of Dabigatran Impurity 71 (C19H20N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dabigatran Impurity 71 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H20N4O3 |
| Molecular Weight | 352.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Related Dabigatran Standards
- Dabigatran Impurity 15 (CAS 1702936-92-2)
- Dabigatran Impurity 22 (CAS 1408238-41-4)
- Dabigatran Impurity 107 (CAS CATO-C4X-1089107)
- Dabigatran Impurity 113 (CAS CATO-C4X-1089113)
- Dabigatran Impurity 100 (CAS CATO-C4X-1089100)
- Dabigatran Impurity 31 (CAS 212322-56-0)
- Dabigatran Impurity 56 (CAS CATO-C4X-108956)
- Dabigatran Impurity 58 (CAS CATO-C4X-108958)
Recommended Standards
- Cefotiam Impurity 2 (CAS 1566599-01-6)
- PDEC-NB (CAS 874302-76-8)
- Valaciclovir EP Impurity D (CAS 1346747-69-0)
- N'-[(1E)-[3-Nitro-4-(pyrrolidin-1-yl)phenyl]methylidene]-2-phenylacetohydrazide (CAS 329777-66-4)
- Bevantolol Impurity 34 (CAS CATO-C4X-241134)
- Azilsartan Impurity 121 (CAS CATO-C4X-1096121)
- Varenicline Impurity 35 (CAS CATO-C4X-196235)
- Edaravone impurity 36 (Mixture of Enantiomers) (CAS CATO-C4X-106236)
- Tert-butyl (s)-(1-(3-bromobenzyl)pyrrolidin-3-yl)carbamate (CAS 1286207-38-2)
- 6,9,12-Hexadecatrienoic acid, ethyl ester (CAS 1469746-36-8)
- Dicycloverine (CAS 77-19-0)
- 5-Amino-3-chloro-2(1H)-pyridinone (CAS 1314916-27-2)
- 2-Chloro-N-(4-(morpholinomethyl)benzyl)acetamide (CAS 885525-89-3)
- [Glu]17-Liraglutide (CAS CATO-C4X-199236)
Why CATO?
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