Rosuvastatin EP Impurity C CAS 1422619-13-3
| CAS No. | 1422619-13-3 |
| Molecular Formula | C22H26FN3O6S |
| Molecular Weight | 479.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 479.52 g/mol gives Rosuvastatin EP Impurity C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Rosuvastatin EP Impurity C (CAS 1422619-13-3, C22H26FN3O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H26FN3O6S, Rosuvastatin EP Impurity C contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 479.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H26FN3O6S |
| Molecular Weight | 479.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- 3-Oxo Rosuvastatin (CAS 1346747-49-6)
- Rosuvastatin Impurity 150 (CAS CATO-C4X-1169150)
- Rosuvastatin Impurity 222 (CAS CATO-C4X-1169222)
- Rosuvastatin Impurity 151 (CAS CATO-C4X-1169151)
- Rosuvastatin EP Impurity G (CAS 1242184-42-4)
- Rosuvastatin 3S, 5S-Isomer (CAS 1584149-34-7)
- Rosuvastatin (CAS 287714-41-4)
- Rosuvastatin Impurity 268 (CAS CATO-C4X-1169268)
Recommended Standards
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
- Benidipine Impurity 61 (CAS CATO-C4X-112061)
- Nicardipine (CAS 55985-32-5)
- Benidipine Impurity 60 (CAS CATO-C4X-112060)
- Josamycin EP Impurity G (CAS 18361-49-4)
- Montelukast Impurity 10 (CAS 150026-75-8)
- Levocarnitine EP Impurity B (CAS 5394-83-2)
- tert-Butyl (2,4-dioxo-1,3-diazaspiro-[4.5]dec-8-yl)carbamate (CAS 1187020-26-3)
- (4-Bromo-2-methyl-6-nitrophenyl)methanamine (CAS 1805141-86-9)
- 3-(2-Ethoxy-5-methylphenyl)isoxazol-5-amine (CAS 501116-38-7)
- 1-(2,3-Dichlorophenyl)-3-(3,4-dimethylphenyl)propan-1-one (CAS 898779-75-4)
- 4-Cyano-3-(difluoromethyl)-2-methylpyridine-6-carbonyl chloride (CAS 1807124-02-2)
- 4-(Difluoromethyl)-2-(hydroxymethyl)-5-(trifluoromethoxy)pyridin-3-ol (CAS 1806727-78-5)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
Why CATO?
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