Montelukast Impurity 10 CAS 150026-75-8
| CAS No. | 150026-75-8 |
| Molecular Formula | C29H28ClNO2 |
| Molecular Weight | 457.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Montelukast Impurity 10 (CAS 150026-75-8, C29H28ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Montelukast Impurity 10 (C29H28ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 457.99 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C29H28ClNO2 |
| Molecular Weight | 457.99 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Montelukast Standards
- Montelukast Impurity 31 (CAS 287930-77-2)
- Montelukast Impurity 47 (CAS 1079753-36-8)
- Montelukast Impurity 49 (CAS CATO-C4X-103149)
- Montelukast Impurity 36 (CAS 142569-69-5)
- Montelukast (3R)-Hydroxy Benzoate (CAS 150026-72-5)
- Montelukast Impurity 19 (CAS 1258428-71-5)
- Montelukast 3-Oxo Benzoate (CAS 149968-11-6)
- Montelukast Impurity 11 (CAS 120578-04-3)
Recommended Standards
- 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol (CAS 142569-70-8)
- 3-((4-Chlorobenzyl)thio)-5-((naphthalen-1-yloxy)methyl)-4-phenyl-4H-1,2,4-triazole (CAS 335218-30-9)
- 2-Amino-4-(4-chlorophenyl)-7,7-dimethyl-3-(4-methylbenzenesulfonyl)-5,6,7,8-tetrahydro-4H-chromen-5-one (CAS 860611-39-8)
- 3-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-4-ethyl-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazole (CAS 344268-92-4)
- Alanyl Glutamine Impurity 2 (CAS CATO-C4X-19742)
- Vonoprazan Impurity 16 (CAS 16133-25-8)
- Flurbiprofen Impurity 128 (CAS 1515948-47-6)
- 8-Methyl-2-vinylquinoline (CAS 52322-00-6)
- 1-Bromo-2-chloro-5-methoxy-3-nitrobenzene (CAS 1263376-18-6)
- (Dansylaminoethyl)-tri-methyl-ammonium perchlorate (CAS 33423-98-2)
- 3-Bromo-1H-pyrazol-5-amine (CAS 1203705-55-8)
- 1-[6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazine (CAS 1193387-25-5)
- N-(2-(1H-Imidazol-1-yl)-2-oxoethyl)acetamide (CAS 50676-30-7)
- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
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