1,3-bis(2-fluorophenyl)propan-2-one CAS 1425-89-4
| CAS No. | 1425-89-4 |
| Molecular Formula | C15H12F2O |
| Molecular Weight | 246.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-bis(2-fluorophenyl)propan-2-one.
1,3-bis(2-fluorophenyl)propan-2-one (CAS 1425-89-4), molecular formula C15H12F2O and molecular weight 246.25 g/mol, is a CATO reference standard with documented purity and traceability.
1,3-bis(2-fluorophenyl)propan-2-one (C15H12F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,3-bis(2-fluorophenyl)propan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12F2O |
| Molecular Weight | 246.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related bis Standards
- 3-(3-Fluorophenyl)-1-(4-fluorophenyl)propan-1-one (CAS 898789-17-8)
- 7-(3-Fluorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1031558-69-6)
- Ethyl 2-((4-fluorophenyl)sulfonyl)acetate (CAS 1037147-97-9)
- 1-(3-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1082437-10-2)
- 1-(2-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 1082584-37-9)
- 1-(4-fluorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid (CAS 123345-03-9)
- Ethyl 2-(3-fluorophenyl)pyrimidine-5-carboxylate (CAS 1240622-63-2)
- Ethyl 2-(2-fluorophenyl)pyrimidine-5-carboxylate (CAS 1245059-88-4)
Recommended Standards
- 2,6-Dimethyl-2',4'-difluorobiphenyl-4-carboxaldehyde (CAS 1350760-27-8)
- 2-(3,4-Difluorophenyl)-1-(p-tolyl)ethan-1-one (CAS 1504609-61-3)
- Ethyl 5-(difluoromethyl)-1-isobutyl-1H-pyrazole-4-carboxylate (CAS 1275246-17-7)
- cis-[4-(trifluoromethyl)cyclohexyl]methanesulfonate (CAS 1544010-54-9)
- (1E)-N-(4-{[(4-fluorophenyl)methyl]sulfanyl}phenyl)-1-(thiophen-2-yl)methanimine (CAS 882083-97-8)
- (S)-4-Bromo-5,6,7,8-tetrahydroisoquinolin-8-amine (CAS 1428651-99-3)
- Ethyl-2-chloro-3-cyano-6-methylisonicotinate (CAS 40108-12-1)
- Ethyl 2-((3-amino-2-benzoylbenzofuran-7-yl)oxy)acetate (CAS 301538-61-4)
- 5-Bromo-N-(2-(1-ethyl-1,2,3,4-tetrahydroquinolin-6-yl)ethyl)furan-2-carboxamide (CAS 955792-03-7)
- 5-Amino-3-((4-bromo-2,6-difluorobenzyl)oxy)isothiazole-4-carboxamide (CAS 2436737-00-5)
- 2-[(2-Chloro-4-fluorophenyl)methoxy]-2,3-dihydro-1H-isoindole-1,3-dione (CAS 321430-34-6)
- 4-(Chloromethyl)-2-(3-fluorophenyl)thiazole (CAS 953736-97-5)
- Diethyl 2-aminopyrimidine-4,5-dicarboxylate (CAS 62328-20-5)
- Cycloaspeptide D (CAS 691363-62-9)
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