Phloroglucinol impurity 61 CAS 14262-07-8
| CAS No. | 14262-07-8 |
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 334.36 g/mol gives Phloroglucinol impurity 61 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Phloroglucinol impurity 61 (CAS 14262-07-8) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22O6 and a molecular weight of 334.36 g/mol.
Phloroglucinol impurity 61 (C18H22O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Phloroglucinol impurity 61 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Phloroglucinol Standards
- Phloroglucinol impurity 46 (CAS CATO-C4X-221746)
- Phloroglucinol Impurity 43 (CAS 72046-73-2)
- Phloroglucinol Impurity 76 (CAS CATO-C4X-221776)
- Phloroglucinol Glucuronide (CAS 50602-76-1)
- Phloroglucinol impurity 47 (CAS CATO-C4X-221747)
- Phloroglucinol Impurity 37 (CAS CATO-C4X-221737)
- Phloroglucinol Impurity 40 (CAS CATO-C4X-221740)
- Phloroglucinol Impurity 41 (CAS 62218-04-6)
Recommended Standards
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- Mycophenolate Mofetil EP Impurity E (CAS 31858-66-9)
- Travoprost Impurity 27 (CAS CATO-C4X-192527)
- Loratadine Impurity 59 (CAS CATO-C4X-142659)
- Telithromycin impurity 1 (CAS CATO-C4X-27601)
- 2-(Fluoromethyl)pyrimidin-5-ol (CAS 1391733-75-7)
- 1-(tert-Butyl)2-methylazepane-1,2-dicarboxylate (CAS 1352305-12-4)
- 5-Fluoro-3,6-dihydro-2,6-dioxo-3-(tetrahydro-2-furanyl)-1(2H)-pyrimidineacetic acid (CAS 872103-36-1)
- tert-Butyl (4-(4-bromobenzamido)cyclohexyl)carbamate (CAS 1286272-80-7)
- 1,4-dioxaspiro[4.5]decan-8-ylhydrazine dihydrochloride (CAS 1630725-37-9)
- Methyl 1-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]-1H-pyrazole-3-carboxylate (CAS 1707586-20-6)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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