Phloroglucinol impurity 47 CAS CATO-C4X-221747
| CAS No. | CATO-C4X-221747 |
| Molecular Formula | C16H10O6 |
| Molecular Weight | 298.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Phloroglucinol impurity 47.
As a process- or degradation-related impurity, Phloroglucinol impurity 47 (CAS CATO-C4X-221747, C16H10O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Phloroglucinol impurity 47 (C16H10O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10O6 |
| Molecular Weight | 298.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Phloroglucinol Standards
- Phloroglucinol Glucuronide (CAS 50602-76-1)
- Phloroglucinol Impurity 62 (CAS CATO-C4X-221762)
- Phloroglucinol Impurity 74 (CAS CATO-C4X-221774)
- Phloroglucinol Impurity 75 (CAS CATO-C4X-221775)
- Phloroglucinol Impurity 79 (CAS CATO-C4X-221779)
- Phloroglucinol Impurity 39 (CAS CATO-C4X-221739)
- Phloroglucinol Impurity 2 (CAS 61524-51-4)
- Phloroglucinol Impurity 42 (CAS CATO-C4X-221742)
Recommended Standards
- Ioversol Impurity 25 (CAS CATO-C4X-209125)
- Pentoxyverine impurity 19 (CAS CATO-C4X-227019)
- Rhein Methylate (CAS 6155-37-9)
- Uridine Impurity 23 (CAS CATO-C4X-233423)
- Betamethasone Impurity 142 (CAS CATO-C4X-1437142)
- Cefminox Impurity 23 (CAS 74228-11-8)
- Carfilzomib Impurity 27 (CAS CATO-C4X-102227)
- DMAC-PDB (CAS 663599-04-0)
- 4-(Phenoxymethyl)-1,3-dioxolan-2-one (CAS 4437-83-6)
- (3-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol (CAS 1422655-38-6)
- Tert-butyl 4-(aminomethyl)-4-(azepan-1-yl)piperidine-1-carboxylate (CAS 1305711-99-2)
- Methyl 2-(chlorosulfonyl)-3-methylbenzoate (CAS 126535-26-0)
- Tris(trimethylsiloxy)silane (CAS 1873-89-8)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
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