Irinotecan Impurity 54 CAS 142677-15-4
| CAS No. | 142677-15-4 |
| Molecular Formula | C22H22N2O6 |
| Molecular Weight | 410.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Irinotecan Impurity 54 (CAS 142677-15-4) is a certified pharmaceutical impurity reference standard with the molecular formula C22H22N2O6 and a molecular weight of 410.42 g/mol.
Based on its molecular formula C22H22N2O6, Irinotecan Impurity 54 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 410.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22N2O6 |
| Molecular Weight | 410.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Irinotecan Standards
- Irinotecan Impurity 64 (CAS CATO-C4X-166764)
- Irinotecan Impurity 26 (CAS 2438258-39-8)
- Irinotecan Impurity 22 (CAS 124622-81-7)
- Irinotecan Impurity 60 (CAS CATO-C4X-166760)
- Irinotecan EP Impurity G (CAS 947687-01-6)
- Irinotecan impurity 57 (CAS CATO-C4X-166757)
- Irinotecan Impurity 52-D5 (CAS 718612-51-2)
- Irinotecan Hydrochloride Trihydrate EP Impurity E (CAS 86639-52-3)
Recommended Standards
- Doxazosin EP Impurity C (CAS 617677-53-9)
- benzhydryl (7R)-7-amino-3-(chloromethyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (CAS CATO-C4X-179854)
- Rivaroxaban Impurity 121 (CAS 1855920-51-2)
- Ceftibuten (CAS 97519-39-6)
- Verteporfin Impurity 6 (CAS CATO-C4X-35496)
- Rosuvastatin EP Impurity J (Sodium Salt) (CAS 2226413-62-1(Free Acid))
- Azithromycin EP Impurity A (CAS 76801-85-9)
- 3-(4-Fluorophenyl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603067-22-7)
- AZD 0328 (CAS 220099-91-2)
- Imetit dihydrobromide, 95% (CAS 102203-18-9)
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(2-methoxybenzamido)-4-methylthiophene-3-carboxylate (CAS 505096-67-3)
- Trans-3-(2,2-Dichloroethenyl)-N,N-diethyl-2,2-dimethylcyclopropanecarboxamide (CAS 153653-46-4)
- 1-Cyano-n-cyclopropylmethanesulfonamide (CAS 1249212-61-0)
- [D-His]-Semaglutide B (x TFA Salt) (CAS CATO-C4X-2226117)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com