Azithromycin EP Impurity A CAS 76801-85-9
| CAS No. | 76801-85-9 |
| Molecular Formula | C37H70N2O12 |
| Molecular Weight | 734.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Azithromycin EP Impurity A (C37H70N2O12) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Azithromycin EP Impurity A (CAS 76801-85-9), a pharmacopoeial impurity reference standard (molecular formula C37H70N2O12, MW 734.96 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Azithromycin EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C37H70N2O12 |
| Molecular Weight | 734.96 g/mol |
| Purity | >93% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 2 |
Related Azithromycin Standards
- Azithromycin EP Impurity C (CAS 620169-47-3)
- Azithromycin EP Impurity I (CAS 172617-84-4)
- Azithromycin EP Impurity B (CAS 307974-61-4)
- Azithromycin impurity 53 (CAS 152727-04-3)
- Azithromycin CP Impurity Q (CAS 99290-97-8)
- Azithromycin CP Impurity R (CAS 161193-44-8)
- Azithromycin Impurity 23 (CAS CATO-C4X-100323)
- Azithromycin Impurity 50 (CAS CATO-C4X-100350)
Recommended Standards
- N-Despropyl Gamithromycin (CAS 145388-07-4)
- Pyridinium, 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-ethyl- (CAS 149270-91-7)
- （See C4X-100319）Azithromycin EP Impurity A (See C4X-100319) (CAS CATO-C4X-10037)
- Erythromycin Impurity 23 (CAS 226086-79-9)
- Acetaminophen Impurity 32 (CAS 874-60-2)
- Alectinib Impurity 63 (CAS CATO-C4X-283663)
- Epinephrine /Adrenaline impurity 98 (CAS CATO-C4X-184998)
- Ethyl 2-(2-methoxyphenyl)cyclopropane-1-carboxylate (CAS 1017553-79-5)
- Methyl (R)-3-chloro-2-hydroxypropanoate (CAS 82971-67-3)
- Tedizolid Impurity 91 (CAS 1259078-16-4)
- 1-(piperidin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid hydrochloride (CAS 1955554-72-9)
- 6-(Cyclohexyloxy)-1H-purine (CAS 120503-68-6)
- Aripiprazole Impurity 76 (CAS CATO-C4X-100876)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com