Ethyl 5-amino-4-bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate CAS 1427022-87-4
| CAS No. | 1427022-87-4 |
| Molecular Formula | C13H11BrF3N3O2 |
| Molecular Weight | 378.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 5-amino-4-bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 5-amino-4-bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate (CAS 1427022-87-4), molecular formula C13H11BrF3N3O2 and molecular weight 378.14 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 5-amino-4-bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate (C13H11BrF3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 5-amino-4-bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11BrF3N3O2 |
| Molecular Weight | 378.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- ethyl 5-amino-1-[4-bromo-3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylate (CAS 1186404-53-4)
- (5-Amino-1-(2,4-difluorophenyl)-1H-pyrazol-4-yl)(4-bromophenyl)methanone (CAS 618091-69-3)
- 6-Amino-4-(3-iodophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 293759-02-1)
- N-(2-((6-Amino-9H-purin-2-yl)thio)ethyl)-2-iodoacetamide (CAS 146269-93-4)
- 3-Amino-8-bromo-1-(pyridin-4-yl)-1H-benzo[f]chromene-2-carbonitrile (CAS 1272756-34-9)
- 2-Amino-7-bromo-4-(pyridin-3-yl)-4H-benzo[g]chromene-3-carbonitrile (CAS 882747-31-1)
- N-(3-(4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-5-yl)allyl)-2,2,2-trifluoroacetamide (CAS 96102-27-1)
- 5-[2-amino-3-(methoxycarbonyl)-1H-pyrrolo[2,3-b]quinoxalin-1-yl]-2-hydroxybenzoic acid (CAS 499229-16-2)
Recommended Standards
- (S)-N-[3-(3-Fluoro-4-iodo-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide (CAS 149524-45-8)
- N-[(2,5-dichloro-3-pyridyl)carbonyl]-N'-[3-(trifluoromethyl)phenyl]urea (CAS 680216-68-6)
- 3-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluorobenzoic acid (CAS 1426531-27-2)
- 6-chloro-N'-(3-chlorobenzoyl)-4-(trifluoromethyl)nicotinohydrazide (CAS 287979-15-1)
- 3-(2-Hydroxypropyl)pyrrolidin-2-one (CAS 1566752-37-1)
- 1-(3,4-Dichlorobenzyl)-4-(4-fluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-40-2)
- 5-Nitro-1-phenyl-1H-pyrazolo[3,4-b]pyridine-3-carbaldehyde (CAS 88796-44-5)
- 2-Benzylisoquinolin-2-ium bromide (CAS 23277-04-5)
- (E)-N'-(1-(4-aminophenyl)ethylidene)-3-chlorobenzohydrazide (CAS 304456-58-4)
- 1-(3-Methoxybenzyl)imidazolidin-2-one (CAS 1140242-92-7)
- (2-Bromo-6-(piperidin-4-yl)pyridin-4-yl)boronic acid (CAS 2225176-56-5)
- N1-([1,1'-Biphenyl]-2-yl)-N2-benzyloxalamide (CAS 1909333-78-3)
- 2-(3,3-Dimethylbut-1-yn-1-yl)-1,3-dioxolane (CAS 904815-50-5)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
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