N-[(2,5-dichloro-3-pyridyl)carbonyl]-N'-[3-(trifluoromethyl)phenyl]urea CAS 680216-68-6
| CAS No. | 680216-68-6 |
| Molecular Formula | C14H8Cl2F3N3O2 |
| Molecular Weight | 378.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies N-[(2,5-dichloro-3-pyridyl)carbonyl]-N'-[3-(trifluoromethyl)phenyl]urea (CAS 680216-68-6), a certified reference material (molecular formula C14H8Cl2F3N3O2, MW 378.13 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-[(2,5-dichloro-3-pyridyl)carbonyl]-N'-[3-(trifluoromethyl)phenyl]urea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 378.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2F3N3O2 |
| Molecular Weight | 378.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
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- 4,5-dichloro-2-[2,6-dichloro-4-(trifluoromethyl)phenyl]pyridazin-3(2H)-one (CAS 110386-48-6)
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- 2,4-Dichloro-1-(4-chloro-3-fluorophenyl)-5-(2,6-difluorophenyl)-1H-imidazole (CAS 1146718-91-3)
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Recommended Standards
- 6-chloro-N'-(3-chlorobenzoyl)-4-(trifluoromethyl)nicotinohydrazide (CAS 287979-15-1)
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- 3-(Perfluorohexyl)propanol (CAS 80806-68-4)
- Ethyl 5-amino-4-bromo-1-(4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylate (CAS 1427022-87-4)
- 4-Mercapto-1H-benzo[d]imidazol-2(3H)-one (CAS 548458-10-2)
- N-(2-bromo-5-fluorophenyl)formamide (CAS 1395493-19-2)
- 1-(2-Chloro-6-fluorobenzyl)piperidine-2-carboxylic acid (CAS 1039264-43-1)
- Tin, [[4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzenaminato]](2-)]-, (SP-4-1)- (CAS 1448009-07-1)
- 4-Bromo-N-ethylaniline hydrochloride (CAS 855949-09-6)
- 1991-52-2 593E9T2MWH 2,5-Di-tert-butyl-4-hydroxyanisole 2,5-Di-tert-butyl-4-methoxyphenol CCRIS 5220 EINECS 217-873-0 UNII-593E9T2MWH (CAS 1991-52-2)
- 1-(2,4-Dimethoxyphenyl)-4,4,4-trifluorobutane-1,3-dione (CAS 82529-67-7)
- Azide-PEG3-C1-Ala (CAS 2054345-67-2)
- Silybin (CAS 22888-70-6)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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