5-Aminoisothiazole-4-carbonitrile CAS 1427502-13-3
| CAS No. | 1427502-13-3 |
| Molecular Formula | C4H3N3S |
| Molecular Weight | 125.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Aminoisothiazole-4-carbonitrile is closely related to a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Aminoisothiazole-4-carbonitrile (CAS 1427502-13-3), molecular formula C4H3N3S and molecular weight 125.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, sulfur-containing functionality, 5-Aminoisothiazole-4-carbonitrile is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 125.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H3N3S |
| Molecular Weight | 125.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Aminoisothiazole Standards
- 5-Aminoisothiazole-3-carbonitrile (CAS 1368194-55-1)
- 4-Aminoisothiazole-3-carboxamide (CAS 4592-54-5)
- 4-Aminoisothiazole-5-carboxamide (CAS 533937-83-6)
- 5-Aminoisothiazole-3-carboxylic acid (CAS 1416374-24-7)
- 4-Aminoisothiazole-3-carboxylic acid (CAS 462067-90-9)
- 5-Aminoisothiazole-3,4-dicarbonitrile (CAS 100326-56-5)
- 3-Aminoisothiazole (CAS 4592-62-5)
- Methyl 5-aminoisothiazole-3-carboxylate, 96% (CAS 1094070-51-5)
Recommended Standards
- 3-Methyl-1,2,4-thiadiazole-5-carbonitrile (CAS 1490714-51-6)
- 4-Aminothiazole-2-carbonitrile (CAS 1198154-95-8)
- 2-hydroxyethanesulfonamide (CAS 162894-76-0)
- Orforglipron impurity 25 (CAS 443-86-7)
- 1-Oxa-2,7-diazaspiro[4.4]non-2-ene-3-carboxylic acid (CAS 1215034-84-6)
- 4-Chloro-2-(tetrahydrofuran-2-yl)pyrido[3,4-d]pyrimidine (CAS 1437435-22-7)
- 3-(5-Chlorobenzo[d]oxazol-2-yl)aniline (CAS 293737-77-6)
- 5-Amino-3-ethyl-1-phenyl-1H-pyrazole-4-carbonitrile (CAS 50427-83-3)
- N-[1-(Naphthalen-2-yl)ethyl]hydroxylamine (CAS 111525-02-1)
- 5-Amino-2,6-dimethylquinoline (CAS 116632-59-8)
- Ethyl 6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1000844-18-7)
- 5-Bromo-2-chlorophenoxy(tert-butyl)dimethylsilane (CAS 1881291-40-2)
- 2-Bromo-4-chloro-6-(trifluoromethoxy)aniline (CAS 1244949-24-3)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
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