Orforglipron impurity 25 CAS 443-86-7
| CAS No. | 443-86-7 |
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Orforglipron impurity 25 is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Orforglipron impurity 25 (CAS 443-86-7) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8FN and a molecular weight of 125.14 g/mol.
Based on its molecular formula C7H8FN, Orforglipron impurity 25 contains a nitrile group, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 125.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Orforglipron impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Orforglipron Standards
- Orforglipron impurity 28 (CAS 35270-87-2)
- Orforglipron impurity 36 (CAS 1092961-07-3)
- Orforglipron impurity 121 (CAS 2212021-39-9)
- Orforglipron Impurity 113 (CAS CATO-C4X-3234113)
- Orforglipron Impurity 43 (CAS 2025595-61-1(free base))
- Orforglipron Impurity 63 (CAS 2212021-57-1)
- Orforglipron Impurity 115 (CAS CATO-C4X-3234115)
- Orforglipron impurity 27 (CAS 465529-57-1)
Recommended Standards
- Flupirtine Impurity 8 (CAS 140-75-0)
- 4-Aminothiazole-2-carbonitrile (CAS 1198154-95-8)
- 2-Fluorobenzylamine (CAS 89-99-6)
- 5-Aminoisothiazole-3-carbonitrile (CAS 1368194-55-1)
- Phloroglucinol Impurity 75 (CAS CATO-C4X-221775)
- Triptorelin Impurity (Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) (CAS CATO-C4X-186211)
- Moxifloxacin impurity 201 (CAS CATO-C4X-1074201)
- 4-Bromobut-2-enamide (CAS 118941-93-8)
- Relebactam Impurity 121 (CAS CATO-C4X-2144121)
- N-Benzylguanidine (CAS 2211-57-6)
- tert-Butyl (4-(dimethyl(oxo)-λ6-sulfanylidene)-3-oxo-1-phenylbutan-2-yl)carbamate (CAS 676486-20-7)
- 2-(3-propoxyphenyl)ethan-1-amine (CAS 103686-13-1)
- Lurasidone Impurity 38 (CAS 55745-83-0)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com