6-Bromo-8-fluoro-1-methyl-3,4-dihydroquinolin-2(1H)-one CAS 1427588-36-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1427588-36-0
Molecular FormulaC10H9BrFNO
Molecular Weight258.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-8-fluoro-1-methyl-3,4-dihydroquinolin-2(1H)-one CAS 1427588-36-0 chemical structure

Description

6-Bromo-8-fluoro-1-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 1427588-36-0), molecular formula C10H9BrFNO and molecular weight 258.09 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 6-Bromo-8-fluoro-1-methyl-3,4-dihydroquinolin-2(1H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 258.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Bromo-8-fluoro-1-methyl-3,4-dihydroquinolin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H9BrFNO
Molecular Weight258.09 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Br-containing
Nitrogen Atoms1

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