2,4-Dichloro-5-(2-thienyl)thieno[2,3-d]pyrimidine CAS 1428139-55-2
| CAS No. | 1428139-55-2 |
| Molecular Formula | C10H4Cl2N2S2 |
| Molecular Weight | 287.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,4-Dichloro-5-(2-thienyl)thieno[2,3-d]pyrimidine (C10H4Cl2N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2,4-Dichloro-5-(2-thienyl)thieno[2,3-d]pyrimidine (CAS 1428139-55-2), a certified reference material (molecular formula C10H4Cl2N2S2, MW 287.19 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,4-Dichloro-5-(2-thienyl)thieno[2,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H4Cl2N2S2 |
| Molecular Weight | 287.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Dichloro Standards
- 2,6-Dichloro-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridine (CAS 1496582-60-5)
- (2,6-Dichloro-3-(trifluoromethyl)phenyl)trimethylsilane (CAS 871254-70-5)
- 11,12-Dichloro-9,10-dihydro-9,10-prop[1]enoanthracene (CAS 20852-67-9)
- 2,2-Dichloro-N-(4-(piperidin-1-yl)phenyl)acetamide (CAS 860609-06-9)
- (2,3-Dichloro-4-methoxyphenyl)(thiophen-3-yl)methanone (CAS 55901-81-0)
- (2,3-Dichloro-4-methoxyphenyl)-2-thienylmethanone 2,3-Dichloro-4-methoxyphenyl 2-thienyl Ketone 40180-05-0 (CAS 40180-05-0)
- 4,6-dichloro-3-methyl-1-(oxan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1346447-97-9)
- 2,2'-Dichloro diphenyl disulfide (CAS 31121-19-4)
Recommended Standards
- 2,2,2-Trifluoro-N-(7-oxo-6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-yl)acetamide (CAS 138621-69-9)
- 1-Methyl-4-nitro-3-(3-trifluoromethyl-phenoxy)-1h-pyrazole (CAS 1443279-25-1)
- 2,2,2-Trifluoroethyl N-(2-oxo-2H-1-benzopyran-6-yl)carbamate (CAS 1354961-77-5)
- (5-Bromo-2-(2-ethylbutoxy)phenyl)methanol (CAS 1444177-08-5)
- 4-Chloro-5-methylpyrrolo[2,1-f][1,2,4]triazine (CAS 529508-56-3)
- 2-Ethoxy-5-(1-tosylpyrrolidin-2-yl)pyridine (CAS 1352509-32-0)
- 2-(4-(Benzyloxy)-2-ethyl-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1825308-37-9)
- Dimethyl 5-Cyanoisophthalate (CAS 23340-69-4)
- Lusutrombopag Impurity 53 (CAS CATO-C4X-208453)
- 2-Cyclopropyl-1-(piperazin-1-yl)ethan-1-one (CAS 1339181-87-1)
- 2-Chloro-3-(piperidin-1-yl)quinoxaline (CAS 32998-26-8)
- 3-(4-Fluorophenyl)-1,2-thiazole (CAS 1429330-65-3)
- [1-(propan-2-yl)-1h-pyrazol-5-yl]methanol (CAS 1007488-73-4)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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