(2,6-Dichloro-3-(trifluoromethyl)phenyl)trimethylsilane CAS 871254-70-5
| CAS No. | 871254-70-5 |
| Molecular Formula | C10H11Cl2F3Si |
| Molecular Weight | 287.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 287.18 g/mol gives (2,6-Dichloro-3-(trifluoromethyl)phenyl)trimethylsilane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies (2,6-Dichloro-3-(trifluoromethyl)phenyl)trimethylsilane (CAS 871254-70-5), a certified reference material (molecular formula C10H11Cl2F3Si, MW 287.18 g/mol) for analytical method development and quality control.
The molecular framework of (2,6-Dichloro-3-(trifluoromethyl)phenyl)trimethylsilane (C10H11Cl2F3Si) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11Cl2F3Si |
| Molecular Weight | 287.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
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- 2,2-Dichloro-N-(4-(piperidin-1-yl)phenyl)acetamide (CAS 860609-06-9)
- 2,4-Dichloro-5-(2-thienyl)thieno[2,3-d]pyrimidine (CAS 1428139-55-2)
- (2,3-Dichloro-4-methoxyphenyl)(thiophen-3-yl)methanone (CAS 55901-81-0)
- (2,3-Dichloro-4-methoxyphenyl)-2-thienylmethanone 2,3-Dichloro-4-methoxyphenyl 2-thienyl Ketone 40180-05-0 (CAS 40180-05-0)
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Recommended Standards
- 7-Bromo-4-(tert-butoxy)thieno[3,2-d]pyrimidine (CAS 1964517-60-9)
- (2-Chloro-4-fluorobenzyl)(4-chlorophenyl)sulfane (CAS 903125-31-5)
- N-[(2,5-Dichlorophenyl)methyl]piperidine-2-carboxamide (CAS 190509-38-7)
- (2-Chloro-6-fluorobenzyl)(4-chlorophenyl)sulfane (CAS 712300-00-0)
- [(2,6-Difluorophenyl)methyl]boronic acid (CAS 2246550-95-6)
- 1-(4-Bromopyridin-3-yl)-N,N-dimethylpiperidin-4-amine (CAS 1707604-99-6)
- n-(3,5-Dichlorobenzyl)-2-ethoxyethan-1-amine (CAS 1179159-99-9)
- Dehydroandrosterone Acetate (CAS 5223-99-4)
- Ethyl 7-bromothieno[2,3-c]pyridine-2-carboxylate (CAS 1835288-51-1)
- 1-(5-bromo-2-furyl)ethanone (CAS 3199-50-6)
- 2-Chloro-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]ethan-1-one (CAS 158939-09-4)
- 3-Hexenal (CAS 4440-65-7)
- N-Benzyl-4-chloropyrimidin-2-amine (CAS 71406-63-8)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
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