(3R,4S)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid CAS 1428243-36-0
| CAS No. | 1428243-36-0 |
| Molecular Formula | C14H17NO4 |
| Molecular Weight | 263.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(3R,4S)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid (CAS 1428243-36-0) is a high-purity analytical reference standard with the molecular formula C14H17NO4 and a molecular weight of 263.29 g/mol.
The molecular framework of (3R,4S)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid (C14H17NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (3R,4S)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17NO4 |
| Molecular Weight | 263.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3S,4R)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid (CAS 1428243-35-9)
- (3S,4R)-1-Cbz-4-methylpyrrolidine-3-carboxylic Acid (CAS 1428243-71-3)
- N-(2-Methoxyethyl)-2-(3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)acetamide (CAS 1428139-02-9)
- 3-[(1E)-[2-(Quinolin-8-yl)hydrazin-1-ylidene]methyl]phenol (CAS 1429220-53-0)
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