Tenofovir Impurity 60 CAS 1428470-49-8
| CAS No. | 1428470-49-8 |
| Molecular Formula | C30H34N10O7P2 |
| Molecular Weight | 708.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tenofovir Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tenofovir Impurity 60 (CAS 1428470-49-8) is a certified pharmaceutical impurity reference standard with the molecular formula C30H34N10O7P2 and a molecular weight of 708.60 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir Impurity 60 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 708.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C30H34N10O7P2 |
| Molecular Weight | 708.60 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 10 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 118 (CAS CATO-C4X-1076118)
- Tenofovir monopyrfuroxil enrutabine adduct (CAS CATO-C4X-1076107)
- Tenofovir dipivuroxime enrutabine adduct (CAS 1962114-98-2)
- Tenofovir alafenamide impurity 81 (CAS CATO-C4X-179781)
- Tenofovir Impurity 83 (CAS CATO-C4X-107683)
- Tenofovir Impurity 125 (CAS 1796931-18-4)
- Tenofovir disoproxil Impurity 13 (CAS 1244022-54-5)
- Tenofovir Alafenamide Impurity 37 (CAS CATO-C4X-179737)
Recommended Standards
- 12,12,13,13,14,14,15,15,16,16,17,17,17-Tridecafluoroheptadecyl dimorpholinophosphinate (CAS 134051-91-5)
- Flomoxef Impurity 44 (CAS CATO-C4X-138244)
- 4,5-Bis(1,3,2-dithiarsolan-2-yl)-3,6-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9-[9H]xanthene]-5-carboxylic acid (CAS 439791-28-3)
- TPB26-2Br (CAS 1392832-46-0)
- Sitagliptin Impurity 24 (CAS CATO-C4X-114424)
- Pyridoxine Impurity 50 HCl (CAS CATO-C4X-187750)
- Risedronate EP Impurity A (CAS 1486617-90-6)
- 2-Amino-3-(1-benzothiophen-3-yl)propanoic acid (CAS 72170-71-9)
- Hexakis(2,2-difluoroethoxy)phosphazene (CAS 186817-57-2)
- 4-(4-Nitrophenylazo)phenol (CAS 1435-60-5)
- 4-Chloro-1-methylpyrimidin-2(1H)-one (CAS 136308-22-0)
- 6-(Ethoxymethyl)-1H-indole (CAS 1056169-04-0)
- N-{2-[(thietan-3-yl)amino]ethyl}ethane-1-sulfonamide (CAS 1865377-95-2)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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