Tenofovir alafenamide impurity 81 CAS CATO-C4X-179781

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-179781
Molecular FormulaC24H30N10O7P2
Molecular Weight632.51 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tenofovir alafenamide impurity 81 CAS CATO-C4X-179781 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 632.51 g/mol gives Tenofovir alafenamide impurity 81 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Tenofovir alafenamide impurity 81 (CAS CATO-C4X-179781) is a certified pharmaceutical impurity reference standard with the molecular formula C24H30N10O7P2 and a molecular weight of 632.51 g/mol.

Structurally, Tenofovir alafenamide impurity 81 (C24H30N10O7P2) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 632.51 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Tenofovir alafenamide impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC24H30N10O7P2
Molecular Weight632.51 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms10

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