Baxdrostat Impurity 32 CAS 1428651-98-2
| CAS No. | 1428651-98-2 |
| Molecular Formula | C12H15BrN2O |
| Molecular Weight | 283.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Baxdrostat Impurity 32.
Baxdrostat Impurity 32 (CAS 1428651-98-2) is a certified pharmaceutical impurity reference standard with the molecular formula C12H15BrN2O and a molecular weight of 283.16 g/mol.
Structurally, Baxdrostat Impurity 32 (C12H15BrN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 283.16 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Baxdrostat Impurity 32 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15BrN2O |
| Molecular Weight | 283.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Baxdrostat Standards
- Baxdrostat Impurity 34 (CAS 3024295-81-3)
- Baxdrostat Impurity 29 (CAS 1428652-18-9)
- Baxdrostat Impurity 30 (CAS 1428651-83-5)
- Baxdrostat Impurity 39 (CAS 3063824-19-8)
- Baxdrostat Impurity 17 (CAS 3060412-75-8)
- Baxdrostat Impurity 18 (CAS 3060412-98-5)
- (S)-Baxdrostat Impurity 19 (CAS 2649597-45-3)
- Baxdrostat Impurity 31 (CAS CATO-C4X-343431)
Recommended Standards
- Alectinib Impurity 1 (CAS 1256578-99-0)
- 3-Chloro-4-(2-methylpropoxy)benzene-1-sulfonyl chloride (CAS 1016496-31-3)
- Lasmiditan Impurity 3 (CAS 613678-08-3)
- 3-(4-Chloro-3-methylphenoxy)propane-1-sulfonyl chloride (CAS 1018340-71-0)
- Mianserin Impurity 91 (CAS 1192015-20-5)
- Erlotinib Impurity 58 (CAS CATO-C4X-106958)
- rac-Nicotine EP Impurity E (CAS 63551-14-4)
- N-{4-[(E)-2-(1,3-benzothiazol-2-yl)ethenyl]phenyl}-2,4-dichlorobenzamide (CAS 478050-03-2)
- N-Ethyl-2,2-dimethoxyethanamine (CAS 55511-99-4)
- 1-Ethyl-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1119446-11-5)
- Carbonyl[5,10,15,20-tetrakis(2,3,4,5,6-pentafluorophenyl)-21H,23H-porphinato]ruthenium(II) (CAS 171899-61-9)
- 3-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-4-ethyl-4H-1,2,4-triazole (CAS 344273-55-8)
- 3-(3-Nitrophenyl)pyrazole 3-(3-nitro-phenyl)-1h-pyrazole 3-(3-nitrophenyl)-1h-pyrazole 59843-77-5 (CAS 59843-77-5)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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