Alectinib Impurity 1 CAS 1256578-99-0
| CAS No. | 1256578-99-0 |
| Molecular Formula | C13H15BrO2 |
| Molecular Weight | 283.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 283.16 g/mol gives Alectinib Impurity 1 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Alectinib Impurity 1 (CAS 1256578-99-0) is a certified pharmaceutical impurity reference standard with the molecular formula C13H15BrO2 and a molecular weight of 283.16 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, Alectinib Impurity 1 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 283.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Alectinib Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15BrO2 |
| Molecular Weight | 283.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
Related Alectinib Standards
- Alectinib Impurity 48 (CAS CATO-C4X-283648)
- Alectinib Impurity 58 (CAS CATO-C4X-283658)
- Alectinib Impurity 69 (CAS CATO-C4X-283669)
- Alectinib impurity 01 (CAS 1256584-82-3)
- Alectinib Impurity 67 (CAS CATO-C4X-283667)
- Alectinib Impurity 3 (CAS 1256584-73-2)
- Alectinib Impurity 91 (CAS CATO-C4X-283691)
- Alectinib impurity 27 (CAS CATO-C4X-283627)
Recommended Standards
- Lasmiditan Impurity 3 (CAS 613678-08-3)
- Baxdrostat Impurity 32 (CAS 1428651-98-2)
- Domperidone Impurity 30 (CAS CATO-C4X-142030)
- 3-Chloro-4-(2-methylpropoxy)benzene-1-sulfonyl chloride (CAS 1016496-31-3)
- Regorafenib Impurity 53 (CAS CATO-C4X-104753)
- Dosulepin N-Oxide Sulfoxide hydrochloride (CAS CATO-C4X-33561)
- Iodixanol Impurity 10 (CAS CATO-C4X-166310)
- 5-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2H-tetrazole (CAS 775351-35-4)
- 2-Formyl-5-hydroxybenzenesulfonamide (CAS 1243395-82-5)
- N-(2-Hydroxyphenyl)azepane-2-carboxamide (CAS 1479353-41-7)
- 2-((5-Bromopyridin-3-yl)oxy)ethanamine hydrochloride (CAS 1112983-14-8)
- 6-Chloro-N-(3-ethoxypropyl)-4-pyrimidinamine (CAS 1219976-32-5)
- (3-Ethyloxetan-3-yl)methanamine (CAS 929900-20-9)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com