Baxdrostat Impurity 22 CAS 1428652-32-7
| CAS No. | 1428652-32-7 |
| Molecular Formula | C22H25N3O3 |
| Molecular Weight | 379.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 379.46 g/mol gives Baxdrostat Impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Baxdrostat Impurity 22 (CAS 1428652-32-7), a pharmacopoeial impurity reference standard (molecular formula C22H25N3O3, MW 379.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Baxdrostat Impurity 22 (C22H25N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25N3O3 |
| Molecular Weight | 379.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Baxdrostat Standards
- Baxdrostat N-Oxide (CAS CATO-C4X-34341)
- Baxdrostat Impurity 20 (CAS 1428652-30-5)
- Baxdrostat Impurity 21 (CAS 1428652-31-6)
- Baxdrostat Impurity 23 (CAS 1428652-33-8)
- (S)-Baxdrostat Impurity 24 (CAS 1428652-34-9)
- (S)-Baxdrostat Impurity 25 (CAS 1428652-36-1)
- Baxdrostat Impurity 26 (CAS 1428652-35-0)
- Baxdrostat Impurity 5 (CAS 3062109-53-6)
Recommended Standards
- CAS CATO-C4X-34211 (CAS CATO-C4X-34211)
- Valsartan impurity 19 (CAS CATO-C4X-105719)
- tert-Butyl 4-{5-cyano-[2,3'-bipyridin]-6-yl}-1,4-diazepane-1-carboxylate (CAS 946385-97-3)
- Sudan Red 7B (CAS 6368-72-5)
- Ensifentrine impurity 50 (CAS 39201-71-3)
- Sarpogrelate Impurity 5 (CAS CATO-C4X-29135)
- Metaraminol Impurity 83 (CAS CATO-C4X-225283)
- 2-(3,3-Difluoroazetidin-1-yl)-5-fluoropyridine (CAS 1713163-30-4)
- (Z)-3-(((4-fluorobenzyl)oxy)imino)-1-phenylindolin-2-one (CAS 478261-33-5)
- Benfluralin (CAS 1861-40-1)
- N-([1,1'-Biphenyl]-2-yl)-5-methylisoxazole-3-carboxamide (CAS 145440-86-4)
- 2-(1-Methyl-1H-imidazol-5-yl)-6-oxo-1-propylpiperidine-3-carboxamide (CAS 1955530-21-8)
- 1-[2-Chloro-4-(trifluoromethyl)phenyl]-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796904-73-8)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com