Baxdrostat Impurity 6 CAS 1428652-88-3
| CAS No. | 1428652-88-3 |
| Molecular Formula | C22H23N3O2 |
| Molecular Weight | 361.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Baxdrostat Impurity 6 (CAS 1428652-88-3) is a certified pharmaceutical impurity reference standard with the molecular formula C22H23N3O2 and a molecular weight of 361.45 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Baxdrostat Impurity 6 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 361.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Baxdrostat Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O2 |
| Molecular Weight | 361.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Baxdrostat Standards
- Baxdrostat Impurity 10 (CAS 3084664-96-7)
- Baxdrostat Impurity 11 (CAS 3084664-97-8)
- Baxdrostat Impurity 12 (CAS 3084665-89-1)
- Baxdrostat Impurity 7 (CAS 3059713-66-2)
- Baxdrostat Impurity 8 (CAS 3059712-82-9)
- Baxdrostat Impurity 9 (CAS 3059713-67-3)
- (Rac)-Baxdrostat (CAS 1428652-15-6)
- (S)-Baxdrostat (CAS 1428652-16-7)
Recommended Standards
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- 2-(4-Methoxyphenoxy)-N-((4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methyl)acetamide (CAS 1203195-57-6)
- Miconazole EP Impurity B (CAS 24169-02-6)
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- Dimethylphosphorodithioate (CAS 756-80-9)
- 5-(Isopropyl(methyl)amino)pentan-2-one (CAS 1157479-44-1)
- 5-(2-methoxyphenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine (CAS 677311-06-7)
- Isopropyl 2-chloro-6-(4H-1,2,4-triazol-4-yl)benzoate (CAS 1351385-63-1)
- 1-(5-methylpyridin-2-yl)piperidine-4-carboxylic acid hydrochloride (CAS 1209863-82-0)
- (R)-2-amino-2-(3-fluorobicyclo[1.1.1]Pentan-1-yl)acetic acid (CAS 2198170-51-1)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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