Baxdrostat Impurity 8 CAS 3059712-82-9
| CAS No. | 3059712-82-9 |
| Molecular Formula | C22H23N3O2 |
| Molecular Weight | 361.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 361.45 g/mol gives Baxdrostat Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Baxdrostat Impurity 8 (CAS 3059712-82-9), a pharmacopoeial impurity reference standard (molecular formula C22H23N3O2, MW 361.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Baxdrostat Impurity 8 (C22H23N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O2 |
| Molecular Weight | 361.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Nitrogen Atoms | 3 |
Related Baxdrostat Standards
- Baxdrostat Impurity 10 (CAS 3084664-96-7)
- Baxdrostat Impurity 11 (CAS 3084664-97-8)
- Baxdrostat Impurity 12 (CAS 3084665-89-1)
- Baxdrostat Impurity 6 (CAS 1428652-88-3)
- Baxdrostat Impurity 7 (CAS 3059713-66-2)
- Baxdrostat Impurity 9 (CAS 3059713-67-3)
- (Rac)-Baxdrostat (CAS 1428652-15-6)
- (S)-Baxdrostat (CAS 1428652-16-7)
Recommended Standards
- 1-((4-Isopropoxyphenyl)sulfonyl)-4-(pyridin-2-yl)piperazine (CAS 1024523-27-0)
- 2-(4-Methoxyphenoxy)-N-((4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methyl)acetamide (CAS 1203195-57-6)
- 2,3-Dimethoxy-N-((4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methyl)benzamide (CAS 1203263-34-6)
- 1-(2-(2-(4-Fluorophenyl)thiazol-4-yl)ethyl)-3-(thiophen-2-ylmethyl)urea (CAS 1209648-36-1)
- Fluocinolone Acetonide Impurity 24 (CAS CATO-C4X-238124)
- Palonosetron Impurity 43 (CAS CATO-C4X-110543)
- Metaraminol Impurity 74(Mixture of Enantiomers) (CAS 4956-27-8)
- 5,5,5-Trifluoronorvaline (CAS 2365-80-2)
- 5-Fluoro-o-tolyl Isothiocyanate (CAS 175205-39-7)
- 1-(3,4-Dimethoxyphenyl)ethanone (CAS 1131-62-0)
- Diethyl(1-dodecyl)phosphonate (CAS 4844-38-6)
- Fmoc-β-Ala-Hyp（Boc）-OH (CAS CATO-CPTD788459)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(piperidin-4-yl)propanoic acid (CAS 368866-16-4)
- Delicious Peptide (bovine) (CAS 73984-05-1)
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