Axitinib Impurity 6 CAS 1428728-83-9
| CAS No. | 1428728-83-9 |
| Molecular Formula | C44H36N8O2S2 |
| Molecular Weight | 772.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Axitinib Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Axitinib Impurity 6 (CAS 1428728-83-9) is a certified pharmaceutical impurity reference standard with the molecular formula C44H36N8O2S2 and a molecular weight of 772.94 g/mol.
Structurally, Axitinib Impurity 6 (C44H36N8O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 31.0, corresponding to approximately 31 ring(s) or double-bond equivalent(s). With a molecular weight of 772.94 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C44H36N8O2S2 |
| Molecular Weight | 772.94 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 31.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 2 |
Related Axitinib Standards
- Axitinib Impurity 82 (CAS CATO-C4X-107182)
- Axitinib Impurity N2 (CAS 1428728-84-0)
- Axitinib Impurity 57 (CAS CATO-C4X-107157)
- Axitinib Impurity 81 (CAS CATO-C4X-107181)
- Axitinib Impurity 42 (CAS 808142-24-7)
- Axitinib Impurity 30 (CAS CATO-C4X-107130)
- Axitinib Impurity 67 (CAS CATO-C4X-107167)
- Axitinib Impurity 56 (CAS 2690338-63-5)
Recommended Standards
- (S,S,S)-(-)-Xyl-SKP (CAS 1429939-35-4)
- (R,R,R)-(+)-Xyl-SKP (CAS 1429939-31-0)
- Posaconazole Impurity 88 (CAS CATO-C4X-1208188)
- Fmoc-Arg(Pbf)-Pro-NHEt (CAS 1246940-88-4)
- Opicapone Impurity 48 (CAS CATO-C4X-240448)
- Sitagliptin Impurity 44 (CAS 1253055-92-3)
- Valsartan Impurity 131 (CAS CATO-C4X-1057131)
- 2-(Quinolin-8-yloxy)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 88350-41-8)
- (Z)-N'-((4-aminophenyl)sulfonyl)acetimidamide (CAS 5768-68-3)
- 7-Desmethoxy-7-fluoro Elvitegravir (CAS 869893-92-5)
- Relugolix Impurity 61 (CAS CATO-C4X-242961)
- {[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl}amine hydrochloride (CAS 1217095-86-7)
- n-(Cyclopropylmethyl)-n-propylsulfamoyl chloride (CAS 926207-59-2)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com