Esomeprazole Impurity 83 CAS 142885-95-8
| CAS No. | 142885-95-8 |
| Molecular Formula | C10H12N2O4 |
| Molecular Weight | 224.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Esomeprazole Impurity 83 (CAS 142885-95-8, C10H12N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Esomeprazole Impurity 83 (C10H12N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Esomeprazole Impurity 83 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O4 |
| Molecular Weight | 224.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Esomeprazole Standards
- Esomeprazole Impurity 85 (CAS CATO-C4X-111285)
- Esomeprazole impurity 134 (CAS CATO-C4X-1112134)
- Esomeprazole impurity 135 (CAS CATO-C4X-1112135)
- Esomeprazole Impurity 22 (CAS 1422064-00-3)
- Esomeprazole Impurity 110 (CAS 91219-90-8)
- Esomeprazole Impurity 02 (CAS 53065-28-4)
- Esomeprazole impurity 01 (CAS 1525433-40-2)
- Esomeprazole Impurity 27 (CAS 848694-10-0)
Recommended Standards
- D-Gluconic Acid Ethyl Ester (CAS 74421-63-9)
- Gefitinib Impurity 73 (CAS CATO-C4X-111773)
- 90870-20-5 Ethylmethylcarbamic Acid 4-Nitrophenyl Ester N-Ethyl-N-methyl-O-(4-nitrophenyl)carbamate (CAS 90870-20-5)
- Repaglinide EP Impurity A (CAS 220438-80-2)
- Baricitinib Impurity 43 (CAS 1401222-91-0)
- Pranoprofen Impurity 81 (CAS CATO-C4X-181181)
- Atomoxetine Impurity 18 (CAS CATO-C4X-155018)
- Cis-3-Methyl-Piperidine-1,2-Dicarboxylic Acid 1-Tert-Butyl Ester (CAS 123834-09-3)
- 2-Methylnaphthalene-1,4-diyl dibenzoate (CAS 2211-31-6)
- methyl 2-(chlorosulfonyl)-3-nitrobenzoate (CAS 1864061-83-5)
- (11bR)-4-hydroxy-2,6-bis(2,4,6-triethylphenyl)- 4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin (CAS 1221940-52-8)
- 1-Bromo-4-[4-(trifluoromethoxy)phenoxy]benzene (CAS 873203-36-2)
- 5-(Benzyloxy)-1H-pyrrolo[3,2-b]pyridine-2-carbaldehyde (CAS 17288-51-6)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com