Esomeprazole Impurity 22 CAS 1422064-00-3
| CAS No. | 1422064-00-3 |
| Molecular Formula | C9H12ClNO2S |
| Molecular Weight | 233.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Esomeprazole Impurity 22.
CATO supplies Esomeprazole Impurity 22 (CAS 1422064-00-3), a pharmacopoeial impurity reference standard (molecular formula C9H12ClNO2S, MW 233.72 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Esomeprazole Impurity 22 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Esomeprazole Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12ClNO2S |
| Molecular Weight | 233.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Esomeprazole Standards
- Esomeprazole impurity 135 (CAS CATO-C4X-1112135)
- Esomeprazole Impurity 02 (CAS 53065-28-4)
- Esomeprazole Impurity 85 (CAS CATO-C4X-111285)
- Esomeprazole Impurity 83 (CAS 142885-95-8)
- Esomeprazole impurity 01 (CAS 1525433-40-2)
- Esomeprazole impurity 134 (CAS CATO-C4X-1112134)
- Esomeprazole Impurity 110 (CAS 91219-90-8)
- Esomeprazole Impurity 27 (CAS 848694-10-0)
Recommended Standards
- Ticagrelor Impurity 39 (CAS 1431867-40-1)
- Chlorpromazine EP Impurity E (CAS 92-39-7)
- tert-Butyl (5-chlorothiophen-2-yl)carbamate (CAS 63806-71-3)
- 4-Chlorophenothiazine (CAS 7369-69-9)
- Clotrimazole Impurity 18 (CAS 717109-43-8)
- Ampicillin Impurity 47 (CAS CATO-C4X-144347)
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- 7-Chloro-5H-indeno[1,2-c]pyridin-5-one (CAS 114995-34-5)
- 2,4-Dihydro-3H-1,2,4-triazol-3-imine (CAS 65380-04-3)
- 3-Chloro-1-methoxynaphthalene (CAS 861319-58-6)
- 3-(Propan-2-yl)-5-(2,2,2-trifluoroethyl)-1h-1,2,4-triazole (CAS 1249765-50-1)
- 2-(4-Fluorophenyl)-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one (CAS 2248255-17-4)
- tert-Butyl 2-(4-methyl-6-(methylamino)pyridin-3-yl)piperidine-1-carboxylate (CAS 1352519-27-7)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com