2-fluoro-2-(piperidin-3-ylidene)ethan-1-ol CAS 1428976-54-8
| CAS No. | 1428976-54-8 |
| Molecular Formula | C7H12FNO |
| Molecular Weight | 145.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-fluoro-2-(piperidin-3-ylidene)ethan-1-ol is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-fluoro-2-(piperidin-3-ylidene)ethan-1-ol (CAS 1428976-54-8) is a high-purity analytical reference standard with the molecular formula C7H12FNO and a molecular weight of 145.17 g/mol.
The molecular framework of 2-fluoro-2-(piperidin-3-ylidene)ethan-1-ol (C7H12FNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-fluoro-2-(piperidin-3-ylidene)ethan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12FNO |
| Molecular Weight | 145.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluoro Standards
- 9-fluoro-3-oxa-7-azabicyclo[3.3.1]nonane (CAS 1341035-38-8)
- 7-Fluoro-3-oxa-9-azabicyclo[3.3.1]Nonane (CAS 1782547-09-4)
- ((3S)-3-Fluoro-1-azabicyclo[3.2.0]heptan-5-yl)methanol (CAS 2820537-28-6)
- (5-Fluoro-3-azabicyclo[3.1.1]Heptan-1-yl)methanol (CAS 2375269-44-4)
- 2-Fluoro-5-azaspiro[3.4]octan-7-ol (CAS 2817638-77-8)
- 3-Fluoro-1-isopropylpyrrolidin-2-one (CAS 522665-40-3)
- 3-Fluoro-1-propylpyrrolidin-2-one (CAS 522665-39-0)
- 3-fluoro-6-methylpyridine-2-carbaldehyde (CAS 884495-48-1)
Recommended Standards
- (2Z)-3-(Diethylamino)-2-fluoroprop-2-enal (CAS 139680-79-8)
- (2Z)-3-(diethylamino)-2-fluoroprop-2-enal (CAS 152873-64-8)
- 5-Ethyl-3-hydroxy-4-methyl-2(5H)-furanone-d3 (CAS 156420-67-6)
- 4-Acetamidobutanoic acid (CAS 3025-96-5)
- 2-Chloro-1-ethyl-4-nitrobenzene (CAS 42782-54-7)
- 1-(4-(2-Chloro-4-fluorophenoxy)phenyl)ethan-1-ol (CAS 1178039-67-2)
- 1-(2-Fluoroethyl)-1H-1,2,4-triazole (CAS 265643-99-0)
- Midodrine impurity 1 (CAS CATO-C4X-30721)
- 2-tert-Butyl-4-chloropyrimidine-5-carboxylic acid (CAS 1012879-97-8)
- 1-Acetyl-3-bromo-5-fluoroindole (CAS 1375064-67-7)
- Fluorescein-thiourea-PEG2-azide (CAS 1146195-72-3)
- 4-(1-Benzothiophen-2-yl)azetidin-2-one (CAS 776330-83-7)
- Perindopril Impurity 31 (CAS CATO-C4X-125231)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com