4-Amino-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylic acid CAS 1429418-72-3
| CAS No. | 1429418-72-3 |
| Molecular Formula | C6H8FN3O2 |
| Molecular Weight | 173.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Amino-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylic acid (CAS 1429418-72-3), a certified reference material (molecular formula C6H8FN3O2, MW 173.15 g/mol) for analytical method development and quality control.
4-Amino-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylic acid (C6H8FN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 4-Amino-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8FN3O2 |
| Molecular Weight | 173.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 4-Amino-1-(2-fluoroethyl)-1H-pyrazole-5-carboxylic acid (CAS 1429419-54-4)
- (3-Amino-1-methyl-1H-pyrazol-4-yl)dimethylphosphine oxide (CAS 2243511-85-3)
- (5-Amino-1-methyl-1H-pyrazol-4-yl)dimethylphosphine oxide (CAS 2248401-83-2)
- (S)-2-Amino-3-(2-fluoro-1H-imidazol-4-yl)propanoic acid (CAS 50444-78-5)
- (S)-2-Amino-3-(5-fluoro-1H-imidazol-4-yl)propanoic acid (CAS 42310-02-1)
- 2-Amino-3-(2-fluoro-1H-imidazol-4-yl)propanoic acid (CAS 57212-36-9)
- 2-Amino-3-(5-fluoro-1H-imidazol-4-yl)propanoic acid (CAS 57372-70-0)
- Ethyl 2-amino-5-fluoro-1H-imidazole-4-carboxylate (CAS 89676-58-4)
Recommended Standards
- 4-Nitro-2-thiophenecarboxylic Acid (CAS 13138-70-0)
- Oxo(1,3,4-thiadiazol-2-ylamino)acetic acid (CAS 130992-20-0)
- 1-(2-Fluoro-ethyl)-3-methyl-4-nitro-1h-pyrazole (CAS 1443279-36-4)
- (Z)-2-(2,4-Dioxothiazolidin-5-ylidene)acetic acid (CAS 1171128-34-9)
- 4,4-Dimethyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 4875-37-0)
- 7-Chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid (CAS 68302-47-6)
- 5-(2,4-dichlorophenyl)-4-isopropyl-4H-1,2,4-triazole-3-thiol (CAS 91193-84-9)
- 6-(Phenylsulfonyl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 90323-31-2)
- 2-Amino-6-isobutylpyrimidine-4-carboxylic acid (CAS 938458-90-3)
- 7-Bromoquinazoline (CAS 89892-22-8)
- Atrasentan Impurity 154 (CAS 1058404-07-1)
- tert-Butyl 2-(4-aminophenyl)propanoate (CAS 595570-58-4)
- 2-Formyl-1H-indole-3-carboxylic acid (CAS 73126-42-8)
- Des-Pro36-37-Tirzepatide (CAS CATO-CPTD788938)
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