Atrasentan Impurity 154 CAS 1058404-07-1
| CAS No. | 1058404-07-1 |
| Molecular Formula | C33H46N2O6 |
| Molecular Weight | 566.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Atrasentan Impurity 154 (CAS 1058404-07-1, C33H46N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C33H46N2O6, Atrasentan Impurity 154 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 566.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Atrasentan Impurity 154 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C33H46N2O6 |
| Molecular Weight | 566.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 101 (CAS 1059052-04-8)
- Atrasentan Impurity 112 (CAS 1059754-98-1)
- Atrasentan Impurity 140 (CAS 1058349-19-1)
- Atrasentan Impurity 152 (CAS 1058404-01-5)
- Atrasentan Impurity 168 (CAS 1059043-43-4)
- Atrasentan Impurity 169 (CAS 1059043-50-3)
- Atrasentan Impurity 173 (CAS 1059051-91-0)
- Atrasentan Impurity 174 (CAS 1059051-97-6)
Recommended Standards
- 6-Butyl-2-(2-hydroxy-3-(2-phenylpropan-2-yl)-5-(2,4,4-trimethylpentan-2-yl)phenyl)-[1,2,3]triazolo[4,5-f]isoindole-5,7(2H,6H)-dione (CAS 945857-19-2)
- Atrasentan Impurity 175 (CAS 1059051-98-7)
- Hexadecyl β-D-maltopyranoside (CAS 98064-96-1)
- Atrasentan Impurity 181 (CAS 1073590-82-5)
- Amikacin impurity 30 (CAS CATO-C4X-197730)
- Tadalafil Impurity 41 (CAS 185750-07-6)
- Upadacitinib Impurity 137 (CAS CATO-C4X-2405137)
- 2-(4-Hydroxybenzyl)malonic acid (CAS 90844-16-9)
- 3-Amino-N-(3-bromo-4-ethoxyphenyl)benzene-1-sulfonamide (CAS 721916-20-7)
- 2-(Methylthio)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid (CAS 1160569-78-7)
- tert-butyl (1S,4R)-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1932009-15-8)
- 5-amino-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one (CAS 1850358-61-0)
- 6-(Aminomethyl)-4-hydroxypicolinonitrile (CAS 1393543-72-0)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com