Cephalexin Impurity 28 CAS 142975-48-2
| CAS No. | 142975-48-2 |
| Molecular Formula | C11H10N2O3 |
| Molecular Weight | 218.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Cephalexin Impurity 28 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Cephalexin Impurity 28 (CAS 142975-48-2, C11H10N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cephalexin Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10N2O3 |
| Molecular Weight | 218.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Cephalexin Standards
- Cephalexin Impurity 27 (CAS CATO-C4X-126127)
- Cephalexin Impurity 34 (CAS CATO-C4X-126134)
- Cephalexin Impurity 35 (CAS CATO-C4X-126135)
- Cephalexin Impurity 33 (CAS 883835-57-2)
- Cephalexin Impurity 20 (CAS CATO-C4X-126120)
- Cephalexin Impurity 12 (CAS 65870-52-2)
- Cephalexin Impurity 18 (CAS 34632-04-7)
- Cephalexin Impurity 25 (CAS CATO-C4X-126125)
Recommended Standards
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- Isavuconazole Impurity 64 xTrifluoroacetate（Easy to absorb moisture） (CAS 2832083-17-5（free base))
- Venetoclax Impurity 52 (CAS CATO-C4X-249552)
- Safinamide impurity 52 (CAS 100370-27-3)
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- 9,10-Dihydro-9,10-bis(2-carboxyethyl)-N-(4-nitrophenyl)-10,9-(epoxyimino)anthracene-12-carboxamide (CAS 1225023-87-9)
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- 5-Azaspiro[2.5]Oct-7-ene-4,6-dione (CAS 910052-67-4)
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