Venetoclax Impurity 52 CAS CATO-C4X-249552
| CAS No. | CATO-C4X-249552 |
| Molecular Formula | C19H26ClN3O |
| Molecular Weight | 347.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Venetoclax Impurity 52 (CAS CATO-C4X-249552, C19H26ClN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Venetoclax Impurity 52 (C19H26ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Venetoclax Impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H26ClN3O |
| Molecular Weight | 347.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Venetoclax Standards
- Venetoclax Impurity 84 (CAS CATO-C4X-249584)
- Venetoclax Impurity 79 (CAS CATO-C4X-249579)
- Venetoclax Impurity 14 (CAS CATO-C4X-249514)
- Venetoclax Impurity 49 (CAS CATO-C4X-249549)
- Venetoclax Impurity 126 (CAS CATO-C4X-2495126)
- Venetoclax Impurity 130 (CAS CATO-C4X-2495130)
- Venetoclax Impurity 97 (CAS CATO-C4X-249597)
- Venetoclax Impurity 98 (CAS CATO-C4X-249598)
Recommended Standards
- 2-[2-(4-Chlorophenyl)adamantan-2-yl]-N-(2-hydroxyethyl)acetamide (CAS 400085-11-2)
- 1-[(4-tert-Butylphenyl)amino]-3-(4-chlorophenoxy)-2-methylpropan-2-ol (CAS 866156-86-7)
- Sarpogrelate Impurity 27 (CAS CATO-C4X-291327)
- [(4-Chlorophenyl)methyl][2-(3,5-dimethylphenoxy)ethyl](2-methoxyethyl)amine (CAS 866043-09-6)
- Emedastine EP Impurity B (CAS 87233-54-3)
- Paroxetine Impurity 52 (CAS CATO-C4X-103552)
- Sitagliptin Impurity 108 (CAS CATO-C4X-1144108)
- Phytomenadione/Vitamin K1 Impurity 80 (CAS CATO-C4X-220780)
- 2-Bromo-3-methoxy-4-methylpyridine (CAS 1227571-00-7)
- tert-Butyl 7-cyano-4-azaspiro[2.5]octane-4-carboxylate (CAS 2112771-11-4)
- Ibrutinib Impurity 94 (CAS CATO-C4X-106494)
- 5-(5-Isopropylbenzo[d]oxazol-2-yl)-2-methoxyaniline (CAS 640759-16-6)
- 4-(4-Fluorophenyl)-N-phenethyl-3-(1H-pyrrol-1-yl)thiophene-2-carboxamide (CAS 1291852-87-3)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com