Esomeprazole Impurity 46 CAS 143016-70-0
| CAS No. | 143016-70-0 |
| Molecular Formula | C8H10ClNO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Esomeprazole Impurity 46 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Esomeprazole Impurity 46 (CAS 143016-70-0), a pharmacopoeial impurity reference standard (molecular formula C8H10ClNOHCl, MW 208.08 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Esomeprazole Impurity 46 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H10ClNO HCl |
| Molecular Weight | 208.08 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Esomeprazole Standards
- Esomeprazole Impurity 70 (CAS 103876-98-8)
- Esomeprazole Impurity 71 (CAS 1076199-93-3)
- Esomeprazole Impurity 79 (CAS 1080689-87-7)
- Esomeprazole Impurity 116 (CAS 109371-19-9)
- Esomeprazole Impurity 106 (CAS 110464-72-7)
- Esomeprazole Impurity 31 (CAS 1114596-75-6)
- EsoMeprazole (CAS 119141-88-7)
- Esomeprazole EP Impurity F (CAS 119141-89-8)
Recommended Standards
- Linaclotide Impurity 30 (CAS CATO-C4X-210630)
- Melitracen Impurity 5 (CAS 111-18-2)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com