Calcipotriol Impurity 21 CAS 143032-85-3

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.143032-85-3
Molecular FormulaC28H46O2
Molecular Weight414.66 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Calcipotriol Impurity 21 CAS 143032-85-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 414.66 g/mol gives Calcipotriol Impurity 21 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Calcipotriol Impurity 21 (CAS 143032-85-3) is a certified pharmaceutical impurity reference standard with the molecular formula C28H46O2 and a molecular weight of 414.66 g/mol.

Owing to a steroid core, a hydroxyl group, an ether linkage, Calcipotriol Impurity 21 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 414.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Calcipotriol Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC28H46O2
Molecular Weight414.66 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>90%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997

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